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Introduction to GRADE

RECOVER 2020 uses as new evidence evaluation process that aims at producing a more systematic and transparent assessment of the literature while minimizing the burden on the evidence evaluators. The process is based on the GRADE system, which has been widely adopted by clinical guidelines organizations, including the Consensus on Science with Treatment Recommendations (CoSTR) generated by the International Liaison Committee on Resuscitation (ILCOR). GRADE prescribes an iterative approach to assess the quality of evidence and to formulate a clinical recommendation.